Introduction

Zoleta is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used a... View More

Uses of Zoleta

• Breast cancer
• Infertility due to anovulation

Side effects of Zoleta

• Fatigue
• Hypercholesterolemia (high cholesterol)
• Increased sweating

How to use Zoleta

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zoleta may be taken with o... View More

How Zoleta works

Zoleta is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen... View More

What if you forget to take Zoleta?

If you miss a dose of Zoleta, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More

Indication

Breast cancer

Administration

May be taken with or without food.

Adult Dose

Oral Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Adult: ... View More

Contraindication

Premenopausal women and children; hypersensitivity.

Mode of Action

Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to i... View More

Precaution

Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in br... View More

Side Effect

Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, ra... View More