Inhouse product
Introduction
Meropen 1gm is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg... View More
Uses of Meropen 1gm
Side effects of Meropen 1gm
How to use Meropen 1gm
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Meropen 1gm works
Meropen 1gm is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them t... View More
What if you forget to take Meropen 1gm?
If you miss a dose of Meropen 1gm, please consult your doctor.
Indication
Cystic fibrosis, Intra-abdominal infections, Meningitis, Skin and skin structure infections, Diabetic foot infection
Administration
IV Administration Administer IV infusion over 15-30 minutes; administer IV bolus over 3-5 minutes
Adult Dose
Intravenous Intra-abdominal infections Adult: 1 g 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Skin and skin structure i... View More
Child Dose
Children: IV 60 mg/kg/day, max 3 g/day q8h 120 mg/kg/day meningitis, max 6 g/day q8h Intravenous Intra-abdominal infections Child: >3mth ?50 kg:... View More
Renal Dose
Renal impairment: CrCl (ml/min) 26-50 Usual dose 12 hrly. 10-25 Half the usual dose 12 hrly. <10 Half the usual dose 24 hrly.
Contraindication
Hypersensitivity to meropenem, other carbapenems. History of anaphylactic reaction to β-lactams (e.g. penicillins, cephalosporins).
Mode of Action
Meropenem is a synthetic carbapenem beta-lactam antibiotic that exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in gm+ve an... View More
Precaution
Patient w/ underlying CNS disorders (e.g. brain lesions, history of seizures. Not recommended for treatment of MRSA. Renal impairment. Childn. Pregnancy... View More
Side Effect
1-10% Constipation (1-7%),Diarrhea (4-5%),Nausea or vomiting (1-4%),Rash (2-3%; includes diaper-area moniliasis in pediatric patients),Headache (2%),In... View More
Interaction
Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures
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