Lopadine Nasal Spray 600 mcg spray

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Generic

Olopatadine Hydrochloride

 

Indications

Olopatadine Nasal Spray is an H1 receptor antagonist used to treat the symptoms of seasonal allergic rhinitis in adults and children aged 6 and above.

 

Pharmacology

Olopatadine, an antihistamine, decreases allergy symptoms by inhibiting the activity of histamine in the body. Olopatadine Hydrochloride is used to treat allergy symptoms such as sneezing, itching, runny nose, and other nasal symptoms. Olopatadine Nasal Spray is made up of 0.6 percent w/v Olopatadine (base) in a nonsterile aqueous solution with a pH of around 3.7. Following the first priming (5 sprays), each metered spray from the nasal applicator provides 100 microliters of aqueous solution containing 665 mcg of olopatadine Hydrochloride, which is comparable to 600 mcg of Olopatadine (base). In addition to benzalkonium chloride (0.01 percent), dibasic sodium phosphate, edetate disodium, sodium chloride, hydrochloric acid and/or sodium hydroxide (to adjust pH), and filtered water, Olopatadine Nasal Spray includes.

 

Dosage

Adults and Adolescents 12 years of age and older: Two sprays per nostril twice daily.

Children 6 to 11 years of age: One spray per nostril twice daily.

Administer Olopatadine Nasal Spray by the intranasal route only.

 

Administration

How to use the Nasal Spray-

  • Shake the bottle gently and remove the dust cover.
  • Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
  • Gently blow the nose to clear the nostrils.
  • Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
  • Breathe out through your mouth.
  • Repeat the above steps in the same/ other nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-

  • Remove the dust cover.
  • Gently pull off the nasal applicator.
  • Wash the applicator and dust cover in warm water.
  • Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
  • Gently push the applicator back on the top of the bottle and re-fix the dust cover.

 

Interaction

The interaction with other medicines has not been studied.

 

Side Effects

It is possible to have a bitter taste in the mouth, nosebleeds, or nasal irritation/soreness. Drowsiness is uncommon. Inform your doctor or pharmacist right once if any of these side effects continue or worsen.

 

Pregnancy & Lactation

Pregnancy Type C. There have been no appropriate and well-controlled trials in pregnant women. In pregnant women, Olopatadine Nasal Spray should be used only if the possible benefit to the mother outweighs the potential danger to the embryo or fetus.

Lactation: It is unknown if topical nasal treatment will result in enough systemic absorption to generate measurable amounts in human breast milk. Nursing women should only take Olopatadine Nasal Spray if the possible benefit to the patient surpasses the potential hazards to the newborn.

 

Precautions & Warnings

Before using, spray Olopatadine Nasal Spray 5 times or until a thin mist emerges. Re-prime Olopatadine Nasal Spray after not using it for more than 7 days by releasing two sprays. Olopatadine Nasal Spray should not be sprayed into the eyes. Patients should be advised not to spray Olopatadine Nasal Spray into their eyes.

 

Therapeutic Class

Anti-histamine nasal sprays

 

Storage Conditions

Keep below 30°C and away from light and moisture. Keep out of children's reach.

 

Pharmaceutical Name

Incepta Pharmaceuticals Ltd.

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