Lijenta-MX Tablet 2.5 mg+1000 mg (8pic)

Brand Nipro JMI Pharmacuticals

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Brand Nipro JMI Pharmacuticals

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Lijenta-MX

Linagliptin INN & Metformin Hydrochloride BP Extended Release
Tablet
Description:

PHARMACOLOGY
Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4), an enzyme that degrades the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide). Thus, Linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin from pancreatic beta (?) cells in a glucose-dependent manner and decreasing the secretion of glucagon from pancreatic alpha (?) cells in the circulation.

Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by an increase in peripheral glucose uptake and utilization.