Indication:

Tazocilin™ 4.5 IV infusion is indicated for the treatment of the following systemic and/or local bacterial infections: Nosocomial pneumonia (moderate to severe), Community-acquired pneumonia (moderate only), Uncomplicated and complicated skin and skin structure infections, including cellulitis, cutaneous abscesses and ischemic/diabetic foot infections, Postpartum endometritis or pelvic inflammatory disease, Appendicitis (complicated by rupture or abscess) and peritonitis. Tazocilin™ 4.5 IV Infusion may also be used in the management of neutropenic patients (adults, adolescents and children) with fever suspected to be due to bacterial infections.

Dosage & Administration:

Piperacillin/Tazobactam may be given by slow intravenous infusion (over 20-30 minutes). The usual dosage for adults and children over 12 years is TazocilinTM 4.5 IV infusion given every eight hours. The total daily dose of Piperacillin/Tazobactam depends on the severity and localization of the infection and can vary from 2.25 gm to 4.50 gm administered every six or eight hours. In neutropenia the recommended dose is Piperacillin/Tazobactam 4.5 gm given every six hours in combination with an aminoglycoside. The duration of therapy should be guided by the severity of the infection and the patient’s clinical and bacteriological progress. In acute infections, treatment with Piperacillin/Tazobactam should be continued for 48 hours beyond the resolution of clinical symptoms or the fever.

Preparation:

Tazocilin™ 4.5 IV infusion: Each combipack contains one vial of powder for IV infusion and 1 bottle of 100 ml normal saline (Solo™), one disposable syringe (20 ml), one infusion set, one butterfly needle, one alcohol pad, and one first aid band.