DESCRIPTION

Presentation

Anacaine HC Cream: Each gram cream contains Lidocaine Hydrochloride BP 30 mg and Hydrocortisone Acetate BP 5 mg.

Description

Lidocaine inhibits the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. Hydrocortisone acetate provides relief from inflammatory and pruritic manifestations.

Indications

Anacaine Cream is used for the anti-inflammatory and anesthetic relief form itching, pain, soreness and discomfort due to hemorrhoids, anal fissures, anal pruritus and similar conditions of the anal area.

Dosage & Administration

Anacaine cream should be applied to the affected area(s) twice daily or as directed by physician. Applicator tip should be gently inserted into the anal area (areas of discomfort and anal opening). Applicator and tube should not completely insert in the anus or rectum.

Side Effects

During or immediately following application of Anacaine Cream, there may be transient stinging or burning from open areas of skin, or transient blanching (lightening), or erythema (redness) of the skin.

Precautions

If infection occurs, the drug should be discontinued. Systemic absorption may occur when extensive areas are treated and may cause suppression of hypothalamic-pituitary-adrenal (HPA) axis; avoid using for prolonged periods or with occlusive dressings. Caution should be used with impaired hepatic function and patients taking class I antiarrhythmics.

Use in Pregnancy & Lactation

Pregnancy: Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women.

Lactating Mothers: It is not known whether this drug is excreted in human milk.

Pediatric Use

Safety and efficacy in pediatric patients have not been established.

Drug Interaction

Anacaine HC Cream should be used with caution in patients receiving antiarrhythmic drugs of Class I (e.g., disopyramide, procainamide, quinidine etc), other corticosteroids/immunosuppressant drugs (e.g., cyclosporine, prednisone etc).

Storage

Store at controlled room temperature of 15°C to 30°C, protect from freezing. Keep out of the reach of children.

Commercial Pack

Anacaine HC Cream: Each tube contains 30 gm cream.

A detachable applicator is included in each package.